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Clinical Studies on Hydrogen Water: Benefits & Findings

Hydrogen Water Overview

Hydrogen-rich water (HRW), as produced by molecular hydrogen supplementation found in re:vitalize’s best-selling Hydro:Active, has been the subject of multiple clinical studies exploring its effects on aging, metabolism, liver health, injury and athletic recovery, and cognitive function. Below is an overview of key research findings, summarizing the purpose, results, and implications of each study.

Table of Contents

1. Hydrogen Water and Body Composition in Overweight Adults

Overview: This 12-week study focused on the effects of hydrogen-rich water intake on body composition, short-chain fatty acid turnover, and brain metabolism in overweight adults.

Findings: Participants who consumed hydrogen water regularly experienced improvements in body composition, including reduced body fat and better muscle tone. Additionally, changes in short-chain fatty acids and enhanced brain metabolism were observed, indicating potential benefits for both physical and cognitive health.

Implications: Hydrogen-rich water may help support weight management and improve metabolic health in overweight individuals, while also promoting brain function.

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2. Hydrogen-Rich Water and Gut Health in Overweight Adults

Overview: This study examined how hydrogen-rich water affects gut health by measuring fecal propionic acid levels in overweight adults. Propionic acid is a short-chain fatty acid linked to improved gut health and metabolism.

Findings: Participants who consumed hydrogen-rich water showed higher levels of fecal propionic acid, suggesting that hydrogen-rich water may support a healthier gut microbiome. This increase in propionic acid could be beneficial for metabolism and overall digestive health.

Implications: Hydrogen-rich water may help improve gut health and metabolic function in overweight individuals by promoting beneficial short-chain fatty acids.

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3. Anti-Aging Effects of Hydrogen Water

Overview: This six-month study examined whether hydrogen-rich water could slow cellular aging in older adults. Researchers measured telomere length and DNA methylation patterns, both of which are indicators of biological aging.

Findings: Participants who consumed hydrogen water regularly maintained their telomere length better than those who did not. Additionally, improvements in DNA methylation were observed, suggesting that hydrogen-rich water may support cellular longevity. Many participants also reported better sleep quality and general well-being.

Implications: Hydrogen water may have anti-aging properties at a molecular level, potentially helping individuals maintain overall health as they age.

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4. Hydrogen Water and Metabolic Health

Overview: A 24-week clinical trial focused on individuals with metabolic syndrome, a condition linked to obesity, high cholesterol, and insulin resistance. The goal was to determine if hydrogen-rich water could improve metabolic markers.

Findings: Drinking hydrogen water led to a reduction in blood sugar levels, cholesterol, and inflammation markers. Some participants also experienced mild weight loss.

Implications: These findings suggest that hydrogen-rich water may help regulate metabolism and could be beneficial for individuals managing metabolic disorders

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5. Hydrogen Water for Liver Health and Non-Alcholic Fatty Liver (NAFLD)

Overview: This four-week study investigated the effects of hydrogen-rich water on individuals with non-alcoholic fatty liver disease (NAFLD). Researchers monitored liver enzyme levels and fat accumulation in the liver.

Findings: Participants who consumed hydrogen water showed improved liver enzyme levels and a reduction in fat deposits within the liver.

Implications: The study suggests that HRW may support liver function and could serve as a complementary therapy for individuals with NAFLD.

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6. Cognitive Performance Under Sleep Deprivation

Overview: Researchers studied whether hydrogen water could enhance alertness and mental performance in sleep-deprived individuals. The study compared hydrogen-rich water’s effects with those of caffeine.

Findings: Both caffeine and hydrogen-rich water initially boosted alertness, but hydrogen-rich water’s effects lasted longer and did not result in an energy crash.

Implications: Hydrogen water may be a beneficial alternative to caffeine for sustaining mental clarity and focus, especially for those experiencing sleep deprivation.

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7. Hydrogen-Rich Water  and Cognitive Function in Coffee Drinkers

Overview: This study explored how hydrogen water affects cognitive performance in habitual coffee drinkers. The goal was to determine whether hydrogen-rich water could enhance brain function alongside or instead of caffeine.

Findings: Participants who drank hydrogen water demonstrated improved cognitive performance and brain metabolism. The study also suggested that hydrogen-rich water could reduce dependence on caffeine for maintaining focus and alertness.

Implications: Hydrogen water may offer cognitive benefits, particularly for individuals who consume caffeine regularly and want an alternative way to enhance mental performance.

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hydrogen supplements dissolving in water

8. Hydrogen-Rich Water and Metabolic Syndrome

Overview: This 24-week study looked at the effects of hydrogen-rich water on individuals with metabolic syndrome, a condition often linked to obesity, high cholesterol, and high blood sugar.

Findings: Participants who drank hydrogen-rich water saw improvements in cholesterol levels, blood sugar, and other metabolic markers. They also experienced a reduction in body fat and waist size.

Implications: Hydrogen-rich water may help improve metabolic health and could be useful for managing conditions like metabolic syndrome.

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9. The Impact of Hydrogen Water on Liver Function in Non-Alcholic Fatty Liver Disease (NAFLD)

Overview: This four-week study explored the potential benefits of hydrogen water for individuals with non-alcoholic fatty liver disease (NAFLD), focusing on liver health and function.

Findings: Participants who incorporated hydrogen water into their daily routine experienced improved liver enzyme levels and a reduction in fat buildup in the liver.

Implications: This suggests that hydrogen-rich water may contribute to better liver function and could be a beneficial addition to managing NAFLD.

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10. Hydrogen Water and Exercise Capacity in Overweight Women

Overview: This 28-day study focused on how hydrogen-rich water supplementation could affect exercise performance in mid-age overweight women.

Findings: Participants who drank hydrogen water showed significant improvements in exercise capacity, including better endurance and reduced fatigue during physical activity.

Implications: Hydrogen-rich water may be beneficial for improving exercise performance and helping individuals, especially those who are overweight, increase their physical activity levels.

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11. Molecular Hydrogen and Exercise Performance

Overview: This study investigated the effects of acute supplementation with molecular hydrogen on exercise performance, focusing on submaximal exercise levels.

Findings: Participants who consumed molecular hydrogen before exercising showed better endurance and improved recovery times compared to those who took a placebo. They experienced less fatigue and faster recovery during and after exercise.

Implications: Acute supplementation with molecular hydrogen may enhance exercise performance, particularly for endurance activities, and could aid in quicker recovery after physical exertion.

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12. Molecular Hydrogen and Mitochondrial Health in Non-Alcoholic Fatty Liver Disease (NAFLD)

Overview: This study examined the impact of molecular hydrogen therapy on coenzyme Q10 levels and platelet mitochondrial function in patients with non-alcoholic fatty liver disease (NAFLD).

Findings: Participants who received molecular hydrogen therapy showed an increase in coenzyme Q10 levels and improvements in platelet mitochondrial bioenergetics, which are linked to better overall cellular energy production.

Implications: Hydrogen-rich water may help support mitochondrial function and energy production in individuals with NAFLD, potentially aiding in liver health and overall metabolic processes.

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13. Hydrogen-Rich Water and Sperm Quality in Men

Overview: This pilot trial examined the effects of medium-term hydrogen-rich water intake on sperm quality biomarkers in men with normospermia (normal sperm parameters) and oligospermia (low sperm count).

Findings: Participants who drank hydrogen-rich water showed improvements in sperm count and motility, as well as better overall sperm quality compared to those who did not consume hydrogen water.

Implications: Hydrogen-rich water may have potential benefits for male fertility, particularly in improving sperm quality for men with sperm count issues.

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14. Hydrogen Water and Brain Function in Overweight Individuals

Overview: This study investigated how molecular hydrogen affects the brain’s glutamate/GABA-glutamine cycle, which plays a key role in cognitive function, mood regulation, and overall brain health, in overweight individuals.

Findings: Participants who consumed hydrogen water showed improved regulation of the glutamate/GABA-glutamine cycle, which is associated with better brain metabolism, mood balance, and cognitive function. These effects suggest that hydrogen-rich water may help support brain health in overweight individuals.

Implications: Hydrogen water could offer potential cognitive and mood-enhancing benefits, particularly for individuals struggling with weight-related challenges.

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Unlock the Power of Hydrogen for Better Health

At re:vitalize weight loss & wellness, we’re committed to helping you achieve your wellness goals with high quality, science-backed products. Our Hydro:Active Tablets bring the benefits of molecular hydrogen directly to you, supported by the above studies that highlight its potential in enhancing cognitive function, improving metabolic health, and promoting overall vitality. As the science behind hydrogen-rich water continues to evolve, re:vitalize makes it easy for you to experience these transformative effects. Incorporate our Hydrogen Tablets into your daily routine and feel the difference in your energy, mental clarity, and well-being.

Dan Lemoine
Meet the Author Dan LeMoine
Dan is passionate about helping others get healthy and reclaim their best lives. In addition to serving as re:vitalize’s CEO, Dan is a certified holistic nutritionist, with board certifications from both The American Association of Drugless Practitioners and the American Naturopathic Medical Accreditation Board. He and Dr. Abood co-authored their book, Fear No Food, which became an Amazon #1 Best Seller and #1 New Release. Dan’s thought leadership on weight loss, nutrition, and metabolic health has been featured in various outlets like Fox News, Delish.com, 247Health, Prevention, MSN, and Sports Illustrated. Originally from Ohio, Dan and his wife Danae (also a nutritionist and co-founder of re:vitalize) moved to Phoenix in 2017 to open re:vitalize’s Arizona locations.
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